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Nirmatrelvir/Ritonavir Pfizer is taken orally, twice daily for 5 days1Treatment should begin as soon as possible following a positive test and ≤5 days of symptom onset.Nirmatrelvir/Ritonavir Pfizer recommended dosage for 5 consecutive days1Morning Dose
Nirmatrelvir/Ritonavir Pfizer can be taken with or without food
The tablets should be swallowed whole and not chewed, broken, or crushed
If a dose of Nirmatrelvir/Ritonavir Pfizer is missed within 8 hours of the time it is usually taken, the patient should take it as soon as possible and resume the normal dosing schedule. If the patient misses a dose by more than 8 hours, the patient should not take the missed dose and instead take the next dose at the regularly scheduled time. The patient should not double the dose to make up for a missed dose
If a patient requires hospitalization due to severe or critical COVID-19 after starting treatment with Nirmatrelvir/Ritonavir Pfizer, the patient should complete the full 5-day treatment course at the discretion of his/her healthcare provider.
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